| Customization: | Available |
|---|---|
| Application: | Surgery |
| Usage Mode: | Injection |
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Atracurium besilate Powder for injection
| Specification | 25mg/2.5ml 1's/Box |
| Shelf life | 3Years |
| Storage | Store in a cool and dry place below 25ºC, protect from light |
Therapeutic indications
atracurium is a highly selective, competitive or non-depolarising neuromuscular blocking agent which is used as an adjunct to general anaesthesia to enable tracheal intubation to be performed and to relax skeletal muscles during surgery or controlled ventilation, and to facilitate mechanical ventilation in Intensive Care Unit (ICU) patients.
Dose and method of administration
Use in adults
Injection
atracurium is administered by intravenous injection. The dosage range for
adults is 0.3 to 0.6 mg/kg (depending on the duration of full block required) and will provide adequate relaxation for 15 to 35 minutes.
Endotracheal intubation can usually be accomplished within 90 seconds from the intravenous injection of 0.5 to 0.6 mg/kg.
Full block can be prolonged with supplementary doses of 0.1 to 0.2 mg/kg as
required. Successive supplementary dosing does not give rise to accumulation of neuromuscular blocking effect.
Infusion
After an initial bolus dose of 0.3 to 0.6 mg/kg, atracurium can be used to
maintain neuromuscular block during long surgical procedures by administration as a continuous infusion at rates of 0.3 to 0.6 mg/kg/hour.
Use in children
The dosage in children over the age of one month is the same as that in adults on a bodyweight basis.
Use in the elderly
atracurium besilate may be used at a standard dosage in elderly patients. It is
recommended, however, that the initial dose be at the lower end of the range
and that it be administered slowly.
Use in patients with reduced renal and/or hepatic function
atracurium besilate may be used at standard dosage at all levels of renal or hepatic function, including end stage failure.
Use in patients with cardiovascular disease
In patients with clinically significant cardiovascular disease, the initial dose of
TRACRIUM should be administered over a period of 60 seconds.
****Follow all directions given to you by your doctor and pharmacist carefully
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